VALIUM is usually a federal controlled substance (C-IV) mainly because it is made up of diazepam which might be abused or cause dependence. Keep VALIUM in a secure location to circumvent misuse and abuse.
cyclosporine will increase the amount or outcome of diazepam by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.
amobarbital will lower the level or impact of diazepam by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch.
Observe Carefully (1)istradefylline will increase the degree or result of diazepam by impacting hepatic/intestinal enzyme CYP3A4 metabolism.
sage decreases effects of diazepam by pharmacodynamic antagonism. Small/Importance Unknown. Theoretical interaction; some species of sage may trigger convulsions.
Diazepam is usually applied intermittently for the prevention of febrile seizures that will manifest in young children less than 5 years of age.[twenty] Recurrence costs are lessened, but Unintended effects are frequent and the decision to deal with febrile seizures (which are benign in nature) with medication takes advantage of these factors as Section of the analysis.
VALIUM will make you sleepy or dizzy, and might slow your wondering and motor expertise. Don't travel, function heavy equipment, or do other risky functions right up until you know how VALIUM impacts you.
Diazepam may possibly impair the ability to travel cars or operate equipment. The impairment is worsened from the intake of alcohol for the reason that each work as central nervous method depressants.[39]
enasidenib will enhance the level or result of diazepam by influencing hepatic enzyme CYP2C19 metabolism. Use Warning/Keep an eye on. Enasidenib (a weak CYP2C19 inhibitor) may improve systemic exposure of delicate CYP2C19 substrates. Observe and regulate dose of substrate as clinically indicated.
dexamethasone will lower the level or effect of diazepam by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor.
Coadministration of other CNS depressants or Alcoholic beverages intake may well potentiate CNS-depressant results of diazepam
Adjunct use, if apprehension, anxiousness or acute tension reactions current prior to endoscopic strategies
methylprednisolone will lower read more the level or influence of diazepam by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor.
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